Benfotiamine Health Benefits and Side Effects

Last Updated on October 2, 2022 by amin


Can vitamin B1 be harmful?

Toxicity. It is unlikely to reach a toxic level of thiamin from food sources alone. In the setting of very high intakes, the body will absorb less of the nutrient and flush out any excess amount through the urine. There is no established toxic level of thiamin.

How long does it take for benfotiamine to work?

Therapeutic benefits can be seen as early as 3 weeks, with the most significant improvements occurring in patients taking the highest-dose of benfotiamine, that is, 600 mg/day at 6 weeks.

Does benfotiamine lower blood sugar?

Benfotiamine treatment had no significant effect on blood glucose levels.

Is benfotiamine safe long term?

Benfotiamine is generally considered safe for most people when taken at standard doses, though long-term safety has not been studied. In clinical trials, side effects were mild and included gastrointestinal issues and skin reactions [7].

Does vitamin B1 help you sleep?

Vitamin B1 and B2 for sleep Both vitamin B1 and B2 are essential for our bodies in order to convert food into energyand for the production of the sleep hormone, melatonin.

Should I take B1 in the morning or at night?

The best time to take B vitamins is after you wake up. There are also some data suggesting that taking vitamin B in the afternoon can affect your sleep. To avoid a B-complex affecting your sleep, you should take your B vitamins in the morning, preferably with a meal to maximize their absorption.

Why is Methylcobalamin used?

Methylcobalamin is used to treat vitamin B12 deficiency. Vitamin B12 is important for the brain and nerves, and for the production of red blood cells. Methylcobalamin is sometimes used in people with pernicious anemia, diabetes, and other conditions.

Is benfotiamine safe for liver?

Significance: In conclusion, the treatment with thiamine or benfotiamine even 30min after the massive dose of ethanol has proven to be beneficial against liver damage. Improved results were obtained with benfotiamine in relation to oxidative damage from aqueous compartments.

How much B1 should you take for neuropathy?

Dosage. The recommended dose of benfotiamine is 150300 mg twice daily specifically for diabetic peripheral neuropathy.

Can I take vitamin B1 and magnesium together?

Yes, as B vitamins and magnesium don’t compete for absorption inside your body. Indeed, many supplements combine them as a way of simplifying how you monitor your intake. Vitamin B and magnesium work in tandem to: promote normal function of the nervous system and normal psychological function.

Is pyridoxine a prescription?

Pyridoxine taken by mouth (oral) is available without a prescription. Injectable pyridoxine must be given by a healthcare professional.

What is the best form of B1?

Wheat germ, whole wheat, peas, beans, enriched flour, fish, peanuts, and meat are all good sources of vitamin B1.

Is methylcobalamin the same as B12?

Vitamin B12 supplements are typically derived from two sources: cyanocobalamin or methylcobalamin. Both are nearly identical and contain a cobalt ion surrounded by a corrin ring.

Does benfotiamine have side effects?

When taken by mouth: Benfotiamine is likely safe at doses of up to 600 mg daily for up to 24 weeks. Side effects are rare, but some people have reported stomach problems and skin rashes.

How do you get rid of neuropathy in your feet?

To help you manage peripheral neuropathy:

  1. Take care of your feet, especially if you have diabetes. Check daily for blisters, cuts or calluses. …
  2. Exercise. …
  3. Quit smoking. …
  4. Eat healthy meals. …
  5. Avoid excessive alcohol. …
  6. Monitor your blood glucose levels.

How does thiamine deficiency affect the brain?

Summary: A deficiency of a single vitamin, B1 (thiamine), can cause a potentially fatal brain disorder called Wernicke encephalopathy. Symptoms can include confusion, hallucinations, loss of muscle coordination and vision problems. Untreated, the condition can lead to irreversible brain damage and death.

What are the symptoms of low vitamin B1?

Symptoms of thiamine (B1) deficiency

  1. Loss of appetite. Experiencing an atypical loss of appetite can be one of the earliest symptoms of thiamine deficiency. …
  2. Fatigue. …
  3. Irritability. …
  4. Nerve damage. …
  5. Tingling arms and legs. …
  6. Blurry vision. …
  7. Nausea and vomiting. …
  8. Delirium.

Should benfotiamine be taken with food?

It is an amino acid, and it should be taken on an empty stomach, definitely not with protein. Take it an hour before a meal or 2 hours afterwards. The recommended dosage is 2-5 gm/daily.

Who is most at risk for thiamine deficiency?

People with alcohol dependence. In highly industrialized countries, chronic alcohol use disorders appear to be the most common cause of thiamin deficiency [1].

Can vitamin B1 cause high blood pressure?

When the amount of vitamin B1, also known as thiamine exceeds the normal levels in the body, it can cause hypertension or high blood pressure. Similarly, when high doses of vitamin B2, usually referred to as riboflavin is taken, it can cause hypotension or low blood pressure.

Is benfotiamine the same as Sulbutiamine?

Like disulfide derivatives, benfotiamine may be useful for the treatment of acute peripheral syndromes of thiamine deficiency because it is better absorbed than thiamine, but in contrast to sulbutiamine, it seems to be devoid of specific effects on brain function.

Does benfotiamine have side effects?

When taken by mouth: Benfotiamine is likely safe at doses of up to 600 mg daily for up to 24 weeks. Side effects are rare, but some people have reported stomach problems and skin rashes.

What is the main cause of thiamine deficiency?

A diet consisting mainly of white flour, white sugar, and other highly processed carbohydrates can cause thiamin deficiency. At first, people have vague symptoms such as fatigue and irritability, but a severe deficiency (beriberi) can affect the nerves, muscles, heart, and brain.

Does B1 help with sleep apnea?

Results: A marked clinical recovery was seen after administration of high doses of thiamine, coenzyme Q, L-carnitine, and vitamins C and E, combined with effective treatment with continuous positive airway pressure for the underlying severe obstructive sleep apnea (OSA).

Is benfotiamine safe long term?

Benfotiamine is generally considered safe for most people when taken at standard doses, though long-term safety has not been studied. In clinical trials, side effects were mild and included gastrointestinal issues and skin reactions [7].

How do you reverse nerve damage in feet naturally?

Exercise Regular exercise can help to combat pain and improve your overall health. Being active can reduce your blood sugar, which, in turn, can reduce or slow down nerve damage. Exercise also increases blood flow to your arms and legs and reduces stress. These are all factors that help to reduce discomfort and pain.

What are the side effects of thiamine?

Thiamine may cause side effects. Tell your doctor if either of these symptoms is severe or does not go away:

  • flushing.
  • hives.
  • itching.
  • weakness.
  • sweating.
  • nausea.
  • restlessness.

Does Walmart sell benfotiamine?

Doctors Best Benfotiamine 300 mg – 60 ct (Pack of 2) –

Can benfotiamine cause nerve damage?

Our findings suggest that high-dose benfotiamine (300 mg/day) supplementation over 24 months has no significant effects upon peripheral nerve function or soluble markers of inflammation in patients with type 1 diabetes.

How much B1 do you need a day?

How much vitamin B1 do we need? In the U.S., the recommended daily allowance (RDA) of thiamin taken by mouth is 1.2 mg for males and 1.1 mg for females over the age of 18 years. Pregnant or breastfeeding women of any age should consume 1.4 mg each day.

Can I take vitamin B1 everyday?

The amount that should be consumed on a daily basis is called the recommended dietary allowance (RDA). For adult males, the RDA is 1.2 mg daily. For adult females 18 years of age, the RDA is 1 mg daily. For adult females 19 years and older, the RDA is 1.1 mg daily.

Is benfotiamine good for the heart?

Circulation: Heart Failure: Vitamin B1 Analog Benfotiamine Prevents Diabetes-Induced Diastolic Dysfunction and Heart Failure Through Akt/Pim-1Mediated Survival Pathway.

Why is B1 important?

Function. Thiamin (vitamin B1) helps the body’s cells change carbohydrates into energy. The main role of carbohydrates is to provide energy for the body, especially the brain and nervous system. Thiamin also plays a role in muscle contraction and conduction of nerve signals.

Is methylcobalamin safe?

The Natural Medicines Database considers methylcobalamin to be safe when taken in the right dosage. Extremely high vitamin B12 levels have been linked to the development of lung and prostate cancer. It can also be a symptom of adult-onset Still’s disease, a rare auto-inflammatory disease.

Can you overdose on benfotiamine?

Overdose. Data regarding Benfotiamine overdose is limited. Overdose is likely, since the vitamin is fat-soluble and excess of it is remained stashed in the body. In case you suspect an overdose, seek emergency medical care immediately….

Can you take too much folate?

Yes, you can get too much folic acid, but only from man-made products such as multivitamins and fortified foods, such as breakfast cereals. You can’t get too much from foods that naturally contain folate. You should not get more than 1,000 micrograms of folic acid a day, unless your doctor prescribes a higher amount.

What happens if you take too much thiamine?

Thiamine is generally safe. Very high doses may cause stomach upset. Taking any one of the B vitamins for a long period of time can result in an imbalance of other important B vitamins. For this reason, you may want to take a B-complex vitamin, which includes all the B vitamins.

Is benfotiamine safe for kidneys?

Taken together, these data suggest that benfotiamine protects the peritoneal membrane and remnant kidney in a rat model of peritoneal dialysis and uremia. Peritoneal dialysis (PD) is a well accepted alternative to hemodialysis in the treatment of end-stage renal disease.

Is vitamin B1 good for diabetics?

Vitamin B1 or thiamine has long been associated with human health, including the maintenance of a healthy nervous system and improvement of cardiovascular function in the body. Scientific studies have highlighted that vitamin B1 can also help to support individuals with diabetes.

Is B1 the same as thiamine?

Thiamine, also known as thiamin or vitamin B1, is one the of B vitamins. Thiamine helps to turn food into energy to keep the nervous system healthy.

What are the benefits of taking benfotiamine?

What are the benefits of benfotiamine? Benfotiamine supplements help increase thiamine (vitamin B1) levels. 13 Thiamine is key to a healthy nervous system. Some research suggests it helps with diabetes-related nerve damage and the cognitive declines of Alzheimer’s.

Does thiamine help with anxiety?

For anxiety, thiamine has been used successfully at doses of 250 mg/day to treat patients with anxiety disorders, including symptoms manifesting as chronic fatigue, insomnia, nightmares, anorexia, nausea and vomiting, diarrhea or constipation, chest and abdominal pain, depression, aggression, headache, diaphoresis, and …

What is the difference between B12 and B1?

The main difference between vitamin B1 and B12 is that vitamin B1 is required for the nourishment and growth of the cells in the body. While vitamin B12 is a very necessary component in the metabolism process and also in the nervous system functioning. Both vitamins B1 and B12 belong to the B group of vitamins.

Does benfotiamine help with insulin resistance?

Improves fasting endothelial function. Improves parameters of autonomic function in fasting and postprandial state. Improves insulin sensitivity and prevents postprandial increase in insulin resistance.

Does thiamine affect thyroid?

Thyrotoxicosis is a hypermetabolic state in which there is increased utilization of thiamine. Thiamine deficiency has been observed in association with hyperthyroidism.

Thiamine Supplement in Patients With Severe Hyperthyroidism.

Condition or disease Intervention/treatment Phase
Thyrotoxicosis Drug: Thiamine Not Applicable

May 10, 2016

What health problems result from a folate deficiency?

Without enough oxygen, your body can’t work as well as it should. Low levels of folic acid can cause megaloblastic anemia. With this condition, red blood cells are larger than normal.

What does thiamine do for the brain?

Thiamine is an essential cofactor for several enzymes involved in brain cell metabolism that are required for the production of precursors for several important cell components as well as for the generation of the energysupplying molecule ATP.

Can I take benfotiamine with metformin?

Does BENFOTIAMINE+METFORMIN lower blood sugar levels? BENFOTIAMINE+METFORMIN may cause low blood sugar levels (hypoglycaemia) and can make you hungry, dizzy, irritable, confused, anxious, or shaky. Hence, it is advised to take BENFOTIAMINE+METFORMIN with a meal.

Is B1 good for diabetics?

Research shows that high doses of vitamin B1 (thiamine) could reduce kidney disease in people with Type 2 diabetes. In 2007, Diabetes UK-funded research at the University of Warwick showed that people with Type 1 and Type 2 diabetes have around 75 per cent less levels of vitamin B1 than people without diabetes.

What foods contain benfotiamine?

Thiamine, the natural version of benfotiamine, is a B vitamin you get from foods like whole grains, meat, legumes, and nuts.

Who should not take methylcobalamin?

You should not use methylcobalamin if you are allergic to vitamin B12 or cobalt. Tell your doctor if you have ever had: Leber’s disease or other form of optic nerve damage; an iron or folic acid deficiency; or.

Can benfotiamine raise blood pressure?

We found a marked increase in thiamine and thiamine diphosphate in all patients who received benfotiamine (Table 1, both P < 0.001). Diastolic blood pressure (DBP) was also significantly increased in the benfotiamine group (P < 0.01) and was significantly different from the change in the placebo group (P < 0.05).

Which vitamins should not be taken together?

Some vitamins that should not be taken together, or have dosage limitations, include vitamin C with vitamin B-12, vitamin A supplement with vitamin A-rich foods, folic acid (vitamin B9) and vitamin B12, and vitamin E with vitamin K.

Benfotiamine Health Benefits and Side Effects

Is benfotiamine good for tinnitus?

I began reading reports about benfotiamine which is a much higher absorbable form of vitamin B-1. It works for me. It is 6 weeks now and my tinnitus remains 90 percent gone. Hope this works for you.

Is alpha lipoic acid safe?

Alpha-lipoic acid is generally considered safe with little to no side effects. In some cases, people may experience mild symptoms like nausea, rashes, or itching. However, research shows that adults can take up to 2,400 mg without harmful side effects (38).

Does B1 help with nerve pain?

Vitamin B1 (thiamine) provides your nerves with energy to function, while vitamin B6 relieves nerve pain and transmits nerve impulses correctly. Vitamin B12 regenerates the nerves, protecting them from damage. A deficiency in vitamins B12 or B1 may be partly responsible for your nerve pain.

What is the difference between benfotiamine and thiamine?

Benfotiamine is absorbed much better than water soluble thiamine salts. Maximum plasma levels of thiamine are about 5-fold higher after benfotiamine intake and the bioavailability is about 3.6 times as high as that of thiamine hydrochloride and better than that of other lipophilic thiamine derivatives.

What is the generic name of benfotiamine?

Drug Name : Benfotiamine Benfotiamine(Benfogamma) generic is a vitamin, prescribed for Beri Beri, Wenicke-korsakoff syndrome, diabetic neuropathy.

Is benfotiamine good for neuropathy?

A study of 20 patients given 400mg daily of benfotiamine showed improvement in neuropathy scores and decrease in pain complaints over a 3-week period.

Who needs benfotiamine?

Benfotiamine can boost thiamin levels and help prevent them. Some research suggests benfotiamine may block the harmful effects of glycotoxins. 2 Those are found in high-fat meats.

This supplement is also touted as a treatment for:

  • Anxiety.
  • Back pain.
  • Depression.
  • Fibromyalgia.
  • Non-diabetic neuropathy.
  • Sciatica.
  • Thyroid disease.

How long methylcobalamin can be taken?

Fixed dose combination of sustained release pregabalin and methylcobalamin reduces neuropathic pain. Treatment with lipoic acid methylcobalamin for 2-4 weeks is associated with better outcome in nerve conduction velocity and neuropathic symptoms.

Does thiamine help neuropathy?

A study in the developing world found that oral thiamine and pyridoxine were helpful in improving the pain experienced in diabetic peripheral neuropathy as well as improving signs of neuropathy seen on neurological examination.